Skin Disorders Guide

Diagnostic Hallmarks

Distribution: face and extremities (children); groin and genitalia (adults)
Tendency for clustered formation
Central umbilication

Clinical Presentation
Molluscum contagiosum occurs as skin-colored or white papules 2-10 mm in diameter. These papules are firm, smooth surfaced, and dome shaped. Occasionally, these lesions are translucent enough to erroneously suggest vesicle formation. A central umbilication is present in about 25% of [...]

Patients with porphyria cutanea tarda generally present with bullae and erosions on the dorsal surface of the hands. There is no inflammation surrounding the lesions. Blisters on the hands, which are identical with these (but without the accompanying porphyria), occasionally occur in patients taking tetracycline, nalidixic acid, furosemide (Lasix), and certain nonsteroidal anti-inflammatory drugs (NSAlDs). [...]