Skin Disorders Guide

Diagnostic Hallmarks

Distribution: marked predilection for the lower legs
Nonblanchable petechiae
Slightly palpable petechiae
Absence of ecchymoses

Clinical Presentation
The purpuric lesions of leukocytoclastic vasculitis consist entirely of petechiae; ecchymoses are not found. Moreover, since the petechiae form in association with the presence of a perivascular inflammatory infiltrate, the petechiae are usually at least slightly palpable. This accounts [...]

Anaphylaxis, is a medical emergency characterized by the sudden onset of urticaria, angioedema, dyspnea, and hypotension. It is most commonly encountered :1fter the administration of penicillin or the ingestion of shellfish or nuts in persons who have specific IgE antibodies attached to their mast cells as a result of previous sensitization.
The physical urticmias include cholinergic [...]

Eczematous dermatitis disease of the feet may be caused by anyone of the following six processes: dyshidrotic eczema, atopic dermatitis, vesicular tinea pedis, allergic contact dermatitis, irritant contact dermatitis, and stasis dermatitis. The problems in differential diagnosis are quite similar to hand eczema, but recognition is further hampered by the confounding effect of shoes and [...]

ландшафтCourse and Prognosis
Atopic dermatitis is a chronic disease characterized by exacerbations and remissions. A few patients have a single episode and then remain clear indefinitely, but for most individuals, once the initial episode has occurred, future problems may be anticipated.
Individual episodes of atopic dermatitis left untreated generally continue chronically. Treatment, on the other hand, is [...]

Diagnostic Hallmarks

Distribution: areas of solvent exposure or maceration (weak irritant), areas conforming to patient history of specific contact (strong irritant)
Discontinuation of exposure leads to improvement

Presentation
The relatively common problem of irritant contact dermatitis occurs because of environmental damage to the outer layers of the epidermis. Two types of irritant contact dermatitis are recognized that resulting [...]

Almost any skin disease can become secondarily eczematized. Three factors determine the circumstances under which this is likely to happen. First, those patients who are genetically atopic (20% of the population) are particularly likely to initiate the itch-scratch cycle in the presence of almost any dermatologic condition. Second, lesions that occur in areas of sweat [...]

Diagnostic Hallmarks

Distribution: cheeks, arms, legs, and groin (infants), feet and antecubital and popliteal fossae (children, adolescents), hands, feet, ankles and groin (adults)
Presence of the itch-scratch cycle
Minor Criteria - atopy, xerosis, keratosis pilaris, pityriasis alba, and two prominent lower eyelid folds

Clinical Presentation

The distribution pattern, appears to be determined by irritant factors that lead to [...]

Diagnostic Hallmarks

Distribution
(a) location of the lesions suggests a specific contactant
(b) unilateral or asymmetrical distribution suggests external causation
Shape of the lesions suggests a specific contactant to the clinician
Removal of the suspected contactant leads to resolution of the dermatitis
Positive patch test

Clinical Presentaion
The lesions of allergic contact dermatitis are quite different in appearance from those of irritant contact [...]